Peptide therapy is emerging as a promising and encouraging remedy for many human ailments. From anti-aging solutions to the maintenance of metabolic processes, peptide therapy is used to suppress organ rejection after organ transplants or as a weight loss therapy.
A multi-billion dollar industry, peptides are one of the well-suited therapies of the current millennium. They are naturally present in the body and are synthesized in the lab as well. Recyclable by the human body, these short-chain amino acids do not undergo detoxification or leave behind any debris in the system.
What is peptide therapy? What is the role of a peptide in managing disease states? Read on to know.
What is a Peptide?
Peptides are amino acids, linked together in the form of chains. They are the building blocks of proteins. They act as structural components of cells and tissues, hormones, toxins, antibiotics, and enzymes. Being responsible for numerous biological functions in the body, their role is of utmost importance for health and vitality.
There are 20 naturally-occurring amino acids. Their different combinations yield an immense variety of different molecules, each with a specific function.
Peptides must remain in appropriate concentration to deliver activity levels. Their functional delivery is necessary to achieve homeostasis in the body. Our bodies contain over 7000 known peptides. They are directly involved in different bodily functions. These include hormone production, tissue and muscle repair, immune modulation, brain, and central nervous system vigor, libido and sexual health, weight loss, inflammation control, DNA repair, aging, and even antimicrobial effects.
The function of a peptide is dependent on the types of
- amino acids
- their sequence
- the specific shape of the peptide
Peptides often act as hormones or enzymes. They act as biological messengers relaying information between different cells in the body. Some peptides act as transporters. They allow for selective transport of substances into the cell. For example, glucose peptide transporters are responsible for transferring glucose from the blood into cells to be used for energy.
Peptide hormones are vital for many biological functions in the body. For Examples:
- glucagon-like-peptide 1 (GLP-1)
Each peptide interacts with specific receptors on cells. Upon activation, a cascade of reaction starts in the cell that results in the desired reaction.
Peptide enzymes act as a catalyst in many metabolic functions. For example; food digestion, synthesis of cellular structures, etc.
As structural components, peptides are present in muscle and bone cells, providing shape and resilience.
What is Peptide Therapy?
Owing to their immense role in human physiology and biochemistry, peptides are used as medicines to replenish, replace or mimic the functions of naturally-occurring peptides. They are engaged to compete or adjunct the ability of peptides to target cells in a highly potent and selective manner. Because of its uniquely specific effects, safety and efficacy, peptide therapy is heralded as the future of medicine.
According to data figures recorded in January 2015, there were over
- 60 US FDA-approved peptide medications
- 140 peptide drugs under evaluation in clinical trials
- 500 in preclinical development
Most of these peptide drugs are administered via the intradermal route. Other forms of disposition include transdermal creams, nasal sprays, and oral tablets. Presently, the prevalent field for peptide development is of high interest to the pharmaceutical industry: metabolic disease (diabetes), oncology, and cardiovascular disease.
The medical applications of peptide treatment are just as diverse as the types of peptides. It presents a less invasive mechanism to treat ailments like osteoporosis, neuropathy, Lyme disease, chronic inflammation, autoimmune disease, and other chronic degenerative diseases. Many peptide drugs are critical “replacement therapies” that supplement peptide hormones in cases where endogenous levels are inadequate or absent.
Peptide therapy is not something new to our bodies. Our body already synthesizes and makes use of these peptides. There is no reactionary strain on the body as compared to other medicinal or surgical treatment. The fact that the body is not subjected to a foreign or different agent is what makes the peptide treatment so effective and safe.
PT-141 This particular peptide is used for a variety of issues including to enhance libido, enhance sexual satisfaction, increase energy, promote strong erections, & promote tanner skin.
CJC-295 – To increase HGH levels, decrease body fat, increase muscle mass, increase strength, improve energy, improve quality of sleep, enhance physical & mental performance, improve skin elasticity, or aide in connective tissue repair post injury we recommend the CJC-295 peptide.
This renowned infusion is a 30-year old remedy to help maintain and restore your body’s natural balance. This is great if you feel stressed and need some pick me up. It has been known to alleviate a number of health conditions like fatigue, migraines, depression, muscle pain and menstrual cramps.
Common Peptides and Their Therapeutic Role
Thymosin Alpha 1
A common peptide, known for its role in improving the immune status of the body. It is naturally produced by our thymus gland and lymphoid tissues. Owing to its functional ability to protect the body against harmful invading agents, Thymosin Alpha 1 plays an adjunct role with chemotherapy. It has proven the effectiveness in cases of
|Bacterial Infection||Viral Infection||Autoimmune Illness||Immune Deficiency|
|Lyme Disease||Arthritis||Inflammatory Bowel Disease||Lupus|
|Recurrent Cancer||Scleroderma||HIV||Chronic EBV|
|Mold Illness||Chronic Pain||Fibromyalgia||Some Mental Health Conditions|
Peptide CJC 1295
CJC 1295 delivers therapeutic benefits like those of hGH. It is a growth hormone-releasing hormone (GHRH) analog. GHRH stimulates the anterior pituitary to release hGH. So when injected, CJC 1295 causes the release of growth hormone.
CJC 1295 also increases an important growth factor, IGF-1. The latter is helpful in fat loss, lean muscle growth, and enhanced sleep.
GHRH has a half-life of a few minutes after IV injection. CJC 1295 is much more effective because of its ability to remain active in the body for extended periods. It binds to the albumin protein in the blood. Enzymatic action does not degrade this peptide. So the overall therapeutic effect of this peptide therapy enhances many times.
Peptide GHRP 2
Growth hormone-releasing peptide (GHRP) 2 mimics the effects of ghrelin. Also known as the “hunger hormone”, Ghrelin helps
- regulate appetite
- energy distribution
- body metabolism
Ghrelin is the body’s natural binding molecule of the GHRP receptor in the brain. It plays a significant role in hGH secretion and growth regulation.
The peptide treatment using GHRP 2 follow ghrelin’s hGH stimulation. The difference lies in their targeted approach. GHRP 2 stimulates hGH secretion by 7-15 times. It thereby helps increase appetite. At the same time, it acts to decrease fat mass and cholesterol. The application of GHRP 2 is effective in hypercatabolic patients. For example, individuals suffering from critical illness, cancer, AIDS. It helps to replenish lost body mass and improve wellbeing in chronic illnesses.
MGF is an abbreviation of the mechano growth factor. It is a peptide derived from insulin-like growth factor-1 (IGF-1). The latter plays an important role in early childhood development. It delivers anabolic effects when administered at a later age.
MGF encourages the repair and growth of lost tissue. It delivers these results via activating muscle stem cells. It aids the synthesis of proteins essential for tissue growth. This peptide is an ideal treatment for muscle loss.
Collagen Peptide Treatment
Collagen is a protein that is an essential part of the body’s connective tissue. These include skin, hair, nails, bones, and cartilage.
Our body synthesizes collagen as a natural process. Yet with age, its production slows down. This results in the weakening of bones and joints. Our skin sags and signs of aging start to show.
The best source of collagen is from our diet. Over a lifespan, unhealthy dietary habits and disease processes may lead to its scarce intake and depleted replenish. It is here that collagen peptide may help you to have strong bones and beautiful skin.
Collagen peptide treatment replenishes your body with the raw materials. It aids the natural synthesis of collagen in the body. More collagen means a smoother, younger-looking skin. It also helps to keep your joints flexible, even as you age.
Whole collagen protein is difficult to digest. So oral supplements might not work as injectable. Collagen peptide treatment is readily absorbed in the blood. It makes the whole anti-aging regime much quicker, safer and cost-effective.
Creatine Peptide Treatment
If you are a gym enthusiast, you must know Creatine. It is a bodybuilding staple. It works wonders for increasing strength and building more muscle.
After a heavy lift, your power drops off. Any effort seems more difficult. Called the anaerobic threshold. It states a moment where the muscles use up all their stored energy.
What Creatine does is increase the amount of stored energy in your muscles. Oral Creatine supplements help you push for a few extra seconds of explosive power. In addition, Creatine also increases protein synthesis. It helps build about 15% more muscle. A nootropic, Creatine also contributes towards improving memory and reducing mental fatigue.
The problem with Creatine supplements is that they need a loading phase followed by a maintenance dose. The loading phase has its side effects. Headaches, stomachaches, dehydration, and nausea to name a few. Common yet not serious but annoying. Creatine peptide therapy helps in a way that they are bioavailable. It shortens the loading phase and reduces the side effects.
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There are Many More Examples of Peptides
- Thymosin Beta 4
- GHRP 6 Hexarelin
- Melanotan II
- Cerebrolysin, and so on.
They have wide-ranging applications:
- decreasing inflammation
- facilitating healing of bodily injuries
- aiding muscle growth
- assisting fat loss
- improved wake-sleep cycle
- enhancing skin pigmentation
- improving libido
- repairing nerve damage
- supporting cognitive function
Any Side Effects of Peptide Therapy?
There is hardly any treatment available without side effects. With peptides, the chances are rare and intensity is small. These may include:
- itching at the injection site
- dry mouth
- increased hunger
- darkening of moles
- prominent freckles
- weight loss
It is always better to consult with your physician. A proper and detailed assessment is a must to know if peptide therapy is right for you.